Advanced Formulations of Biopharmaceuticals
Autoren: Martin Scholz(1), Stefan R. Schmidt(2), Birgit Schwab(2), Roland Derwand(1), Sabine Hauck(1), (1) Leukocare, (2) Rentschler Biopharma
März 2018 (2 MB)
Poster
High-Density Cell Banking for Intensified Seed Trains
Autoren: Marvin Kadisch, Lisa Weißer, Kurt Russ
March 2018 (3 MB)
Taking Advantage of the Virus Inactivating Effect in Caprylic Acid-Based Impurity Precipitation for Downstream Processes
Autoren: Sabine Faust, Natalie Hörold, Sven Schubert, Anja Trapp, Alexander Faude
Mai 2017 (2 MB)
Single-Use or Multi-Use – How Proper Does It Work in Small-Scale?
Autoren: Stefan Wieschalka, Janine Seidemann, Anja Schäfer, Stefan R. Schmidt
Mai 2017 (4 MB)
Analysis of Product Quality Attributes by MIR Spectroscopy
Autoren: Anne Steinkämper, Ralf Masuch, Kurt Russ
Mai 2017 (2 MB)
Manufacturing of Complex Biobetters: Half-Life Extended Fusion Proteins and Bispecific Molecules
Autor: Stefan R. Schmidt
Januar 2017 (3 MB)
Leveraging HT Product Quality Analysis using Semi-preparative Protein A-HPLC
Autoren: Anja Gerster, Alexander Faude und Dethardt Müller
April 2016 (4 MB)
Molecular Properties of Antibodies and their Derivatives Impacting Manufacturing
Autor: Stefan R. Schmidt
März 2016 (4 MB)
FcγRIII (CD16) and GD2 Binding Assay for an IgG using Surface Plasmon Resonance (SPR; Biacore) as a Surrogate for Evaluation of Antibody-Dependent Cell-mediated Cytotoxicity (ADCC)
Autoren: Marco Bareth, Stefan Stranner, Manfred Schuster, Melanie Krist, Andreas Maier, Philipp Goerttler, Anton Walser
September 2015 (4 MB)
Increased Antibody Yield due to Modification of LC and HC Expression by Gene Regulatory Elements
Autoren: Claas Wodarczyk, Britta Reichenbächer, Andreas Schulze, Janet Köhler, Anja Gerster, Bernd Rehberger, Dethardt Müller
Juni 2015 (1 MB)
Virus Removal by Simple Depth Filtration in a Two-Step Downstream Process for mAb Production
Autoren: Alexander Faude, Mario Metzger, Anja Gerster, Marcus Peiker, Sabine Faust, Sybille Ebert, Sophie Winterfeld, Nicole Mang, Dethardt Müller
Juli 2014 (1 MB)
Setting up transfection-based recombinant AAV production in the iCELLisTM single use fi xed-bed bioreactor
Autoren: Antje Pegel, Jessica Wegele, Marion Kunz, Claudia Küppers, Andreas Schulze, Antje Rößner, Daniel Kreß, Florian Sonntag, Markus Hörer
Oktober 2013 (3 MB)
Novel tools could give stable producer cell lines their break for commercial manufacturing of recombinant AAV vectors
Autoren: Verena Emmerling, Karlheinz Holzmann, Karin Lanz, Jessica Wegele, Stefan Kochanek, Markus Hörer
Oktober 2013 (3 MB)
Accelerating stable recombinant cell line development by targeted integration
Autoren: Bernd Rehberger, Claas Wodarczyk, Britta Reichenbächer, Janet Köhler, Renée Weber, Dethardt Müller
Juni 2013 (3 MB)
Novel approaches to render stable producer cell lines viable for the commercial manufacturing of RAAV-based gene therapy vectors
Autoren: Verena Emmerling, Karlheinz Holzmann, Karin Lanz, Stefan Kochanek, Markus Hörer
Juni 2013 (3 MB)
Fast track API manufacturing from shake flask to production scale using a 1,000 L single use facility
Autoren: Benjamin Minow, Sven Reiser, Peter Rogge
März 2013 (2 MB)