Article in Bioprocess International 14 January 2017 Featured ReportArticle in Bioprocess International 14 January 2017 Featured Report

January 31, 2017 Article in Bioprocess International 14 January 2017 Featured Report

"Single-Use Depth Filters - Application in Clarifying Industrial Cell Cultures"

Given the high cell densities achievable with both mammalian and microbial cell culture processes, primary recovery can be a significant challenge. The authors discuss single-use technologies for harvest clarification-centrifugation, tangential-flow filtration (TFF), and depth filtration - with their different advantages and disadvantages. Through data comparison, the authors conclude that the most promise for resolving processing issues and cost comes through the use of depth filtration.

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